WCDG meets monthly September to May on the 3rd Wednesday of the month. Meetings are public and include a light dinner & social hour followed by a speaker. To join our mailing list, email firstname.lastname@example.org. Follow us on Twitter @WashChrom & LinkedIn.
41st International Symposium on Capillary Chromatography & 14th GCxGC Symposium
Fort Worth, TX on May 14-19, 2017 Visit www.isccgcxgc.com for more information
Monday, March 27, 2017
Joint meeting with WBMSDG
Shimadzu Training Center, 7100 Riverwood Drive, Columbia, MD (Directions)
6:15PM social hour/dinner, 7:15PM presentation
RSVP to Katherine Fiedler at email@example.com
Featured Speaker: Robert N. Cole, Assistant Professor, Johns Hopkins School of Medicine, Baltimore
Title: Adventures of Capillary Electrophoresis in Proteomics, from Top-down to Bottom-up
Abstract: Capillary zone electrophoresis (CE)-MS has become more accessible with robust electrospray interfaces, presenting a potential alternative to LC-MS. CE achieves rapid and high resolution analyte separation based on net charge and hydrodynamic volume. CE is orthogonal to reversed phase LC with additional benefits of low carryover, low (nanogram) sample injection, and rapid sample loading. CE-MS analysis of complex peptide mixtures is challenging due to the seconds-wide elution peaks produced during the rapid separations. However, increases in MS data acquisition speeds warrant re-examination of the role of CE in proteomics. We are evaluating a microfluidic chip-based CE interface (ZipChip, 908 Devices Inc) for top-down analysis of intact proteins, analysis of high charge/high pI peptides, and bottom-up quantification of proteins. Even with major challenges of sample concentration, protein complexity and automation, CEMS has a bright future in protein analysis.
Bio: Dr. Robert Cole is an assistant professor of biological chemistry at the Johns Hopkins School of Medicine. His research focuses on mass spectrometry strategies to characterize proteins and their modifications in malnutrition, neurological diseases and cancer. Dr. Cole serves as the director of the Mass Spectrometry and Proteomics Facility for the Johns Hopkins University School of Medicine and director of the Mass Spectrometry Core for the Johns Hopkins Kimmel Cancer Center. Dr. Cole received his undergraduate degree in zoology/physiology from the University of Massachusetts, Amherst. He earned his M.S. in biology/physiological ecology from the University of South Carolina and his Ph.D. in physiology/neuroscience from Michigan State University. He completed postdoctoral training in glycobiology/neuroscience at the University of Alabama at Birmingham and the Johns Hopkins School of Medicine. He joined the Johns Hopkins faculty in 1998. He is a member of the American Society for Mass Spectrometry, and his work has been recognized with a National Research Service Award from the National Institutes of Health.
2016 Open House & Poster Session
September 22, 2016 at Bethesda North Marriott Conference Center
Congratulations to Sam Choi, our 2016 winner of the Georges Guiochon travel award for best student poster at the WCDG Open House & Poster Session on September 21!
Sam Choi from George Washington University won the award for his outstanding poster on "CE-nanoESI-MS for Untargeted Proteomic Characterization of Single Embryonic Cells and Small Neuron Populations". He will receive complementary travel to a separations-related conference of his choice. Congratulations, Sam!
We also want to acknowledge our Honorable Mentions, Erika Portero and Rosemary Onjiko from George Washington University, and thank all of our poster presenters, vendors, and attendees for making this year's event a success! Download 2016 Program
3rd Annual Chromatography & Separations Community Mixer
March 10, 2015 at Generations Hall New Orleans
2014 Open House & Poster Session